Direct (nonstop) flights from Medellin to Guayaquil
1 airline flys nonstop from Jose Maria Cordova (MDE) to Simon Bolivar International (GYE). It's 649 miles (1,044 km), about 2h in the air. Operated by AVIANCA.
AVIANCA
Route data last updated: May 28, 2026
Airlines with non-stop flights
Alternative Routes
Other ways to fly from Medellin to Guayaquil with one stop · direct emits 120 kg CO₂ per passenger
Looking for the return flight?
GYE → MDE: Flights from Guayaquil to MedellinOther direct flights from Medellin
Direct flights from Guayaquil (GYE)
Frequently Asked Questions
How long is the direct flight from Medellin to Guayaquil?
A nonstop flight from Medellin (MDE) to Guayaquil (GYE) takes approximately 2 hours. The distance is 649 miles (1,044 km).
Which airlines fly nonstop from Medellin to Guayaquil?
Just AVIANCA.
Is there a nonstop flight from Medellin to Guayaquil?
Yes. 1 airline: AVIANCA.
How far is Medellin from Guayaquil?
The flight distance from Medellin to Guayaquil is 649 miles (1,044 km), measured as the great-circle (shortest air) distance. That's roughly the same distance as the length of Italy.
What type of aircraft flies from Medellin to Guayaquil?
At 2h, this route typically uses narrow-body aircraft — Boeing 737 or Airbus A320. Varies by airline.
Do I need a visa to travel from Colombia to Ecuador?
Depends on your passport. Check with the Ecuador embassy or an official visa portal before booking — requirements change.
What is the carbon footprint of a flight from Medellin to Guayaquil?
Roughly 120 kg CO2 per passenger one-way. That's about the same as driving 600 km.
Is the return flight from Guayaquil to Medellin also nonstop?
Yes — nonstop flights run both ways. Flight time may differ slightly due to wind patterns.
When is the cheapest time to fly from Medellin to Guayaquil?
Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. 3-6 weeks ahead is a good window for this route. Use "Check Prices" above to compare.
How early should I arrive at Jose Maria Cordova for this flight?
3 hours before departure for international flights. You need time for check-in, security, and immigration.